Scientists resolve keystone of cilantro’s beneficial effects. New research explains the mechanism behind cilantro’s anticonvulsive benefits.
Cilantro’s taste and culinary flavor may significantly benefit health as its rich in disease-fighting properties.
Traditional Ayurvedic Indian medicine has hailed the cilantro’s benefits for digestion. Modern medicine also addresses some of the plant’s benefits. Several studies in mice have found that the plant Coriandrum sativum has ability to reduce pain and inflammation. Other studies have shown that the herb compound can protect the skin against ultraviolet (UV) B radiation.
Folk medicine has hailed anticonvulsive benefits of cilantro. However, other studies in mice have reported the plant’s antiseizure effects.
In a recent study, the researchers looked at the molecular mechanism behind cilantro’s anticonvulsant effects. The study findings now appear in the FASEB Journal.
The researchers assessed the metabolites of cilantro leaf. They found that the one, the long-chain fatty aldehyde (E)-2-dodecenal, activates potassium channels.
The principal investigator of the study Geoff Abbott, Ph.D., professor of physiology and biophysics at the University of California Irvine School of Medicine concluded that cilantro activates a class of potassium channels in the brain that reduces seizure activity.
“Specifically, we found one component of cilantro, called dodecenal, binds to a specific part of the potassium channels to open them, reducing cellular excitability,” Prof. Geoff Abbott said adding, “This specific discovery is important as it may lead to more effective use of cilantro as an anticonvulsant, or to modifications of dodecenal to develop safer and more effective anticonvulsant drugs.”